Melphalan antitumor activity is through blocking the duplication of DNA of tumor cells.
马法兰、强的松的抗肿瘤主要作用是分别通过阻断DNA的复制和促使其断裂而达到抑制肿瘤细胞生长的目的。
参考来源 - 酞咪哌啶酮联合MP方案治疗多发性骨髓瘤的疗效和副作用观察The results demonstrated that the activity of 8-flavonemethyl nitrogen mustard was similar to that of melphalan.
结果表明,8-黄酮甲基氮芥的活性与美法仑接近。
参考来源 - 黄酮类衍生物的合成及其生理活性研究·2,447,543篇论文数据,部分数据来源于NoteExpress
The common side effect in intravenous melphalan is mucositis.
黏膜炎是静脉马法兰应用后最常见的副反应;
Methods Retrospective analysis for autologous transplant mainly with intravenous melphalan in 43 children with advanced malignant solid tumours was performed in our center.
方法用回顾性分析的方法,对43例以静脉马法兰为主的预处理移植治疗的儿童高危恶性肿瘤临床资料进行分析。
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