abstract:In toxicology, the median lethal dose, LD50 (abbreviation for “lethal dose, 50%”), LC50 (lethal concentration, 50%) or LCt50 (lethal concentration & time) of a toxin, radiation, or pathogen is the dose required to kill half the members of a tested population after a specified test duration. LD50 figures are frequently used as a general indicator of a substance's acute toxicity.
N
the amount of a drug or other substance that, when administered to a group of experimental animals, will kill 50 per cent of the group in a specified time 致死中量
Most importantly, the order said, examiners at the U.S. Patent and Trademark Office determined that the information at issue was irrelevant to patentability, saying it dealt with tests of the medianlethaldose of the drug, not the much lower doses used by consumers.