Of course, the critical areas must becovered, and this must be explained in the rationale. When sterilizing liquidloads studies must be done to define coldest and warmest point formin and maxload.
当然关键区域必须被覆盖到，这个必须在基本原理解释到，当灭菌液体装载验证中必须对最大和最小装载进行测试以确定最冷和最热点。
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