The most oftenest used linkage analysis is Lods method which is based on maximum likelihood ratio test because of the additivity of log_likelihood functon from independent observations.
由于似然函数的可加性，两位点连锁分析最常用的是基于最大似然比检验的LODS法，即对数优势计分法 (log odds scorn,LODS)。
参考来源 - 遗传性疾病基因定位的连锁分析方法·2,447,543篇论文数据，部分数据来源于NoteExpress
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