Matrix metalloproteinases, a group of proteinases, the main contributors of extracellular matrix degradation, participate in the most of the physiological and pathological processes involved in cell migration, proliferation, and matrix remodeling.
能够降解细胞外基质的金属蛋白酶参与了与细胞外基质降解、细胞移行、增殖等有关的所有病理及生理过程。
参考来源 - 金属蛋白酶在大鼠视神经挤压伤的表达及意义·2,447,543篇论文数据,部分数据来源于NoteExpress
Increased deposition of extracellular matrix (ECM) and reduced matrix degradation are the major character of liver fibrosis.
细胞外基质(ecm)的沉积增加和降解减少是肝纤维化的主要特点。
Both can promote cartilage matrix synthesis, inhibition of cartilage matrix degradation, thereby promoting repair of injured joints.
两者均可以促进软骨基质合成,抑制软骨基质分解,从而促进损伤关节的修复。
For the degradable drug contained PLGA system, the drug diffusion coefficient was critically changed due to matrix degradation, and that would complicate the drug release process.
对于可降解plga含药体系,基体降解使药物扩散系数发生极大变化,导致药物释放过程更加复杂。
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