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In any field of endeavor, it is impossible to make a significant contribution without first being strongly influenced by past achievements within that field.

在任何努力领域，如果不首先受到该领域过去成就的强烈影响，就不可能作出重大贡献。

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And nothing else is going to make a significant contribution to it, OK?

并没有什么其他的因素,会对它有明显贡献？

麻省理工公开课 - 热力学与动力学课程节选

"While these businesses are relatively small at present, they have potential to make a significant contribution to earnings in coming years, " says Christy.

FORBES: Hot Mexican Radio (And TV)

Particularly at this time, a bold initiative to expand trade and investment could make a significant contribution to our strategy to strengthen growth and create jobs.

WHITEHOUSE: The White House

The prize is presented to a living person, institution and active public or private bodies that make a significant contribution to defending, disseminating and embodying the values that were the foundations of Henri La Fountain's life and career in support of universal knowledge, international law and democracy.

UNESCO: Apply for UNESCO Prizes