The new regulations will not make an appreciable difference to most people.

新的规定对大多数人将无大影响。

《牛津词典》

Research shows that the fit between an employee's values and a company's values makes a difference to what contribution they make and whether, two years after they join, they're still at the company.

研究表明，员工价值观与公司价值观的契合程度会影响他们对公司做出何种贡献，以及他们在加入公司两年后是否还留在公司。

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Researchers at Duke University scrutinized more than 160 published studies and found an absence of strong evidence that any of these approaches can make a big difference.

杜克大学的研究人员详细核查了160多项已发表的研究，发现并没有强有力的证据表明这些方法中的任意之一能产生重大作用。

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At best the difference such an effort would make in the terrorist threat facing Americans would be slight.

VOA: standard.2009.10.15

Peter is one of those cases in European history where one person's personality and interest does make an enormous difference.

彼得是欧洲历史上那些,凭借自己的个性和喜好,起到重大影响的例子之一

耶鲁公开课 - 欧洲文明课程节选

It is an impressive number, it is very, very large, but it doesn't make a difference.

这只是一个令人印象深刻的数字，它非常非常大，但是没有区别。

麻省理工公开课 - 化学原理课程节选

Organize your community to make a sustained difference in the life of a veteran because that veteran can make an incredible difference in the life of your community.

WHITEHOUSE: Remarks by the President on Veterans Day

He said the text could have been stronger and more comprehensive, but it can still make an important difference.

NPR: Optimism In UN Over 1st Global Arms Trade Treaty

Additionally, make sure that you identify the areas for improvement where your input can make an immediate difference in their performance.

FORBES: The Four Things Young Leaders Must Do to Effectively Lead Older Generations