You could make a real difference to someone's life by leaving them a generous legacy.

你留给某人一大笔遗产就可以真正改变他的生活。

《柯林斯英汉双解大词典》

Together we can make a real difference to the way people shop.

只要一起努力，我们可以改变人们的购物习惯。

youdao

The simplest everyday activities can make a real difference to the environment.

日常的简单活动也会对环境产生重要的影响。

youdao

What about that case? Well, I think if we were doing a matter of physics, as it posed to--sort of psychology Psychologically we understand why, losing weight might make a real difference about how you feel about yourself.

这个案例该如何解释，我认为，如果我们在研究物理问题，或者，心理学问题,从心理学的角度我们明白原因，减肥可以让你,自己感觉非常不一样。

耶鲁公开课 - 死亡课程节选

So 90% of your portfolio is in domestic marketable securities and only 10% is invested in things like real estate or venture capital or private equity -hardly enough to make a difference in terms of the portfolios returns.

于是90%的投资都在本国有价证券中,仅10%用于比如不动产,风险资本或私募股权投资,这一小块几乎对投资回报,没有什么作用

耶鲁公开课 - 金融市场课程节选

Soapbox Science aims to make a real difference to the visibility and perception of women in science.

UNESCO: Soapbox Science: bringing science to the people

They will make a real difference to tenants' bills while contributing to our low carbon commitments.

BBC: Bristol and Bath Science Park gets new solar roof panels

How this money is spent can make a real difference to the lives of London's four million women.

CNN: Why London's mayoral elections matter so much to women