You could make a real difference to someone's life by leaving them a generous legacy.

你留给某人一大笔遗产就可以真正改变他的生活。

《柯林斯英汉双解大词典》

It offers the chance to make a real difference.

它提供机会来做些与众不同的事情。

youdao

I'd never reach enough people to make a real difference.

我将永远无法真正影响到足够多的人。

youdao

What about that case? Well, I think if we were doing a matter of physics, as it posed to--sort of psychology Psychologically we understand why, losing weight might make a real difference about how you feel about yourself.

这个案例该如何解释，我认为，如果我们在研究物理问题，或者，心理学问题,从心理学的角度我们明白原因，减肥可以让你,自己感觉非常不一样。

耶鲁公开课 - 死亡课程节选

It does show that people possess these stereotypes that make a difference in their real-world behavior.

但它表明人们的这些刻板印象,会影响他们在现实生活中的行为。

耶鲁公开课 - 心理学导论课程节选

So 90% of your portfolio is in domestic marketable securities and only 10% is invested in things like real estate or venture capital or private equity -hardly enough to make a difference in terms of the portfolios returns.

于是90%的投资都在本国有价证券中,仅10%用于比如不动产,风险资本或私募股权投资,这一小块几乎对投资回报,没有什么作用

耶鲁公开课 - 金融市场课程节选

Soapbox Science aims to make a real difference to the visibility and perception of women in science.

UNESCO: Soapbox Science: bringing science to the people

"We need an industrial Olympics, with big schemes which can make a real difference, " he said.

BBC: CBI calls for 'industrial Olympics' to boost economy

This type of prosthetic could make a real difference for people suffering with paralyzed limbs.

FORBES: Replacing a Paralyzed Hand With a Bionic One