But in combination with the more usual methods of self-development, it might make a critical difference.

但与较为通常的自我提高的方法结合起来，它就有可能起关键性的作用。

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When I think back on the people who were here to step in for me at a critical moment, I want to make that same kind of difference.

当我会想到那些关键时刻挺我的那些人，我也想做同样性质的事情。

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So there's a critical window of opportunity we have to make an important difference that can affect the lives of literally millions of people, and practice preventive medicine on a global scale.

因此现在是个关键的时刻，我们必须做出重要的改变，这个改变将能够影响上百万人的生命，那就是以全球性的规模，来实施预行医学制度。

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As Sheldon Adelson has shown, a single billionaire donor has the potential to make a critical difference in an American Presidential race.

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Understanding natural disasters is another critical area for sustainable development in which the IGCP can make a difference.

UNESCO: Open Access to Scientific Information

Instead, as a critical thinker, she asked herself what ways she could make even the slightest difference as a college student.

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