I expect to be consulted about major issues.

我认为重大问题必须找我商量。

《牛津词典》

The senator was accused of waffling on major issues.

人们指责参议员在主要问题上立场模糊。

《牛津词典》

His job is to record how politicians vote on major issues.

他的工作就是要记录政治家是如何对重大问题进行投票的。

《牛津词典》

He told ABC's This Week program that he expects the president will pick someone with a liberal record on major issues.

VOA: standard.2009.05.03

There is a bias toward boys or a bias against girls there So you have to look at a lot of things about websites and software You have to look at gender, you have to look at nationality, language, accessibility, so major for issues.

一种对于男孩偏爱却对女孩偏见的态度,因此对于网页和软件,我们必须仔细观察,必须观察性别，国籍，语言，可接近性等一系列重要的问题。

麻省理工公开课 - 媒体、教育、市场课程节选

Foreign Ministry spokeswoman Jiang Yu Tuesday said one of the major issues is money to help developing nations cope with the effects of climate change.

VOA: standard.2009.12.16

And HMO reform and probably prescription drugs for Medicare recipients will be major issues.

CNN: John King: Bush vacation agenda

We basically coordinate on all major issues and we are determined to continue that.

WHITEHOUSE: THE WHITE HOUSE

As a result, there were no major issues in this area at the games.

FORBES: Five IT Lessons from the London 2012 Olympics