Low pay has long been acknowledged as a major issue in the early childhood field.

长期以来，低工资一直被认为是儿童早教领域的一个主要问题。

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The protection and improvement of the human environment is a major issue which affects the well-being of peoples and economic development throughout the world.

人类环境的保护和改善是影响到世界人民幸福和经济发展的主要问题。

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Republicans have promised to make the health care reform law a major issue in mid-term Congressional elections in November.

VOA: special.2010.03.27

And elsewhere in the world, water becomes a major, major issue.

在世界的其他地区,水资源成了一个非常非常重要的问题

耶鲁公开课 - 关于食物的心理学、生物学和政治学课程节选

To guarantee continued support for the war, Lincoln was forced to recognize that the issue of slavery was, in fact,a major issue.

VOA: special.2009.10.08

But certainly we do know that debt is a major issue in this country.

NPR: Women Of Color Lag Behind In Wealth

The war was a major issue in the Aug. 8 defeat of war supporter Sen.

NPR: Bush Defends Iraq Strategy, Resists Call to Leave

In the 1976 presidential election, the conduct of the Cold War was not a major issue.

FORBES: The Economic Philosophy Behind Newt Gingrich's Populist Surge