We are planning to donate money to a charity and want it to have a major impact on people.

我们计划向慈善机构捐款，希望它给人们带来重大的影响。

youdao

youdao

Interestingly, there's some speculation that humans started having a major impact on Earth much earlier, about 8000 years ago.

有趣的是，有一些推测认为，人类对地球产生重大影响的时间要早得多，大约应该在8000年前。

youdao

Even a slowdown at the border would have a major impact on both countries.

VOA: standard.2009.04.30

Community leaders say donating basic goods like milk powder and aspirin, which can be scarce in Cuba, has a major impact for Cuban families struggling to survive under Communist rule.

VOA: standard.2009.10.23

Despite concerns about the impact of reforms on Wall Street, the three major U.S.indexes closed higher on Friday.

VOA: standard.2010.05.21

All of us make choices everyday that have a Major IMPACT on Our Country.. Our World.

FORBES: Fact-Checking Rush Limbaugh: The Real Impact of the Boycott

The new law, Kennedy said, might have a major impact on passing universal health care nationally.

NEWYORKER: Romney��s Dilemma

The decision could have a major impact on the debate over what constitutes cheating in sports.

NPR: Anti-Doping Agency Reviews Low-Oxygen Tents