The company faces major challenges over the course of the next few years.

这家公司今后几年将面临重大的挑战。

《牛津词典》

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Would you consider this task one of your major challenges?

您是否认为此次任务将是您的主要挑战之一？

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Waskow says the major challenges created for many poor countries by climate change, calls for long-term investment.

VOA: standard.2009.12.11

"One of the major challenges is to get qualified teachers to teach in rural schools."

VOA: standard.2010.02.25

Kamrany says entrepreneurs face two major challenges creating an idea and securing funding for it.

VOA: standard.2010.01.31

Participants addressed current major challenges such as rapid population growth, environmental degradation, and climate change.

UNESCO: Ministers discuss skills for green economies and societies at ECOSOC | United Nations Educational, Scientific and Cultural Organization

Some of them are already behind us, successful and not, and some major challenges are ahead.

FORBES: The Digital Transformation Of Finance And What Banks Should Do About It

Russell Mittermeier (RM): We face several major challenges in achieving our conservation objectives, both short and long-term.

FORBES: Conservation International: Stemming the Tide of Environmental Crises, Part One