Major bleeding was encountered during anterior surgery in all 3 patients.

前路手术时三名患者都发生了大出血。

youdao

The difference in major bleeding translated into a 33% lower relative risk with bivalirudin.

用比伐卢定引起严重出血的差异使相对危险度降低33%。

youdao

Intraoperatively, there was no major bleeding and the operation was completed after meticulous hemostasis.

术中未发现大出血，手术止血彻底。

youdao

The anti-coagulants warfarin and heparin can be easily reversed if a patient develops major bleeding.

FORBES: Why Xarelto for ACS was doomed to fail

It did seem to reduce the risk of major heart attacks, but at the expense of major bleeding problems.

FORBES: Why Xarelto for ACS was doomed to fail

Meta-analyses of randomised studies and large observational registries show that radial access reduces procedure access site-related major bleeding compared to femoral access.

FORBES: ESC Gives A Shot In the Arm To Radial Access For PCI Procedures: A New Default?