Invasive SP clinic isolates have high resistant to erythromycin. Simple macrolide antibiotic use is not recommend in clinic.
临床上不建议单独使用大环内酯类抗生素治疗SP感染。
参考来源 - 重庆儿童肺炎链球菌耐药率与大环内酯类抗生素用药频度相关性及其耐药机制研究A novel macrolide antibiotic, Maituolaimycin, was isolated and purified from the fermentation broth of strain Streptomyces regensis 099. Its novel structure based on spectroscopic analysis was determined, molecular weight was 600.03, and molecular formula was identified as C32H44N2O9.
本研究以抑菌活性为指导,从一株链霉菌Streptomyces regensis 099的发酵液中分离提取了一种新型大环内酯类抗生素,分子量600.03,分子式C32H44N2O9,定名为麦拓莱霉素(maituolaimycin),并且确定了一条较为合理的分离纯化工艺路线。
参考来源 - 一种新型大环内酯类抗生素的分离纯化研究·2,447,543篇论文数据,部分数据来源于NoteExpress
Erythromycin is a broad spectrum macrolide antibiotic and clinically used widely.
红霉素是一类广谱大环内酯类抗生素,在临床上具有广泛的应用。
Objective: To study the macrolide antibiotic adverse reaction and safety of drug application.
目的:探讨大环内酯类抗生素的不良反应及用药安全性。
Roxithromycin, a new macrolide antibiotic, has an antibacterial spectrum similar to that of erythromycin.
罗红霉素为新型大环内酯类抗生素,其体外抗菌活性类似于母体化合物红霉素。
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