The structural features and catalytic activities of macrocycles are reviewed.

对大环化合物的结构特点及催化作用进行了综述。

youdao

Synthetic and functional metal-organic macrocycles are important models to realize the process of enzyme catalysis and recognition.

金属-有机大环结构是一类人工合成的，旨在模拟和学习酶催化及识别过程的重要模型。

youdao

The synthesis of the first two arylenealkyne conjugated macrocycles containing long alkylene bridge via Glaser coupling of template-directed tetraacetylenes was reported.

采用模板导向法高产率地合成了两个含长链亚烷基桥的芳炔类共轭大环。

youdao

At the opposite corner are the injectable macrocycles that have to compete in the extracellular space.

FORBES: Innovation Snapshot: Macrocyclic drugs to unlock new therapeutic targets

Macrocycles offer a number of advantages over bigger biologics, including better ligand efficiency, tissue penetration, delivery, and cost.

FORBES: Innovation Snapshot: Macrocyclic drugs to unlock new therapeutic targets

Obviously the most exciting applications would be for macrocycles that are orally active, cell penetrant drugs that open up totally novel, untapped targets.

FORBES: Innovation Snapshot: Macrocyclic drugs to unlock new therapeutic targets