关键词 肺癌 ; 肺癌相关基因 ; 18srRNA ; 半定量 R T 2PCR [gap=1629]Key words lung cancer; lung cancer related gene; 18srRNA ; sem i2quantitative R T 2PCR
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Conclusion FHIT gene may play a role in the regulation of cell proliferation of lung cancer, and the reduction in FHIT expression may be related to the pathogenesis of lung cancer.
结论FHIT基因可能参与肿瘤细胞增殖的调控，FHIT基因表达下降可能与肺癌的发生密切相关。
CONCLUSION: the high amplification of Cyclin D1 and the high deletion of P16 gene is closely related to the high activity of proliferation of lung cancer.
结论：细胞周期素d1的扩增和P 16的缺失与肺癌细胞的高增殖活性密切相关。
The expression level of FHIT gene was closely related to histological classification, cancer cell differentiation, P TNM stages and lymph node involvement in lung cancer patients (P<0.05).
肺癌组织中FHIT基因表达水平降低与肺癌组织学类型、细胞分化程度，患者P TNM分期、淋巴结转移程度存在相关性（P< 0 .0 5） ；
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