The reason was that Mr Brin had recently discovered that he has inherited from his mother a mutation of a gene called LRRK2 that appears to predispose carriers to familial Parkinson’s.

因为布林先生最近发现，他从母亲那里遗传了一个变异的基因LRRK2。 研究显示，变异的LRRK2可能使得有家族患病史的携带者患帕金森氏症的几率增加。

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Here we found that LRRK2 deficiency conferred enhanced susceptibility to experimental colitis in mice.

我们在本研究中发现，LRRK2缺乏能增加实验性小鼠结肠炎之易感性。

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The pathology of PD caused by mutated LRRK2 also includes formation of abnormal deposits, or "inclusions," in the neurons.

由突变lrrk2引发PD的病理学表现也包括在神经元里形成非正常沉积物或者称为内含体。

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