Detects the toxicological action of Aloe by acute toxicity test, maximum dosage and long-term toxicity test.

采用最大给药量及长期毒性测定芦荟毒性作用。

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ConclusionTheacrine has no significant toxicity in long-term toxicity test to rats, which inferrs that the drawing up dose in clinic is safe.

结论苦茶碱长期用药对大鼠无明显毒性，按临床拟用剂量服用是安全的。

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Methods: the toxicity was observed in the acute toxicity test, the long-term toxicity test, the dermal irritation test and the dermal allergy test.

方法：皮肤急性毒性试验，皮肤长期毒性试验，皮肤刺激性试验，皮肤过敏试验。

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