They are highly malignant and demonstrate local invasion as well as distant spread through the CSF.
具有高度恶性，局部浸润，并随脑积液远处播散。
Most patients eventually succumb to the consequences of local invasion and metastatic cancer, and true long-term cures are rare.
绝大多数病人最终死于肿瘤的局部侵犯及远处转移，罕见真正接受长期治疗的病例。
Skin is a barrier that maintains homeostasis and prevents microorganism invasion. Many local and systemic infections following trauma are often related to loss of skin barrier.
皮肤是维持内环境稳定和阻止微生物入侵的屏障，创伤后发生的许多局部及全身感染总是与丧失皮肤屏障有关。
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