中国最大的综合性文献数据库 -维普资讯 关键词: 阿普唑仑 乙醇 肝微粒体 相互作用[gap=929]Key words: Alprazolam; Ethanol; Liver microsomes; Interaction
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rat liver microsomes 大鼠肝脏微粒体
liver microsomes incubation 肝微粒体孵育
Liver-kidney microsomes 肝肾微粒体 ; 抗肝肾微粒体抗体 ; 肝肾微粒体抗体
liver r microsomes 肝微粒体
In addition,the result of HPLC shows that WLP-S-10 200mg/kg inhibited metabolism of acetaminophen in liver microsomes.
HPLC结果显示,WLP-S-10可以抑制肝微粒体对扑热息痛的代谢。
参考来源 - 性腺切除对小鼠脑衰老和脑热休克蛋白表达的作用,及FLZ抗Aβ生成的作用The enzymatic kinetic of CYP2A activity in swine liver microsomes was further examined using coumarin as a probe drug. The inhibitory effects on swine CYP2A activity were also evaluated using five commonly used human CYP inhibitors.
用探针药物香豆素进一步考察猪肝微粒体CYP2A的酶促动力学,评价5种人CYP同工酶常用的选择性抑制剂对猪CYP2A活性的抑制效果。
参考来源 - 喹恶啉类在大鼠、猪和鸡的比较代谢研究·2,447,543篇论文数据,部分数据来源于NoteExpress
The metabolic stability of madecassoside in liver microsomes is good.
羟基积雪草苷在大鼠肝微粒体中的代谢稳定性很高。
Objective:To study activity of cytochrome P450 for human liver microsomes.
目的:为测定人肝细胞微粒体细胞色素P450氧化酶的活性。
ConclusionThe metabolism of DBDCT in rat liver microsomes was faster, suggesting that the liver first-pass effect of the drug may be stronger.
结论DBDCT在大鼠肝微粒体中代谢较快,提示该药可能肝首过效应较强。
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