...6号染色体着丝点周围(16q12)后, 对IBD易感基因的研究如雨后春笋般涌现出来, 研究手段也是日新月异, 从连锁分析(linkage studies)、全基因组关联分析(genome-wide association, GWA)到基因芯片(microarray)的运用, 取得一系列瞩目的成绩, 本文就此作一综述.
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genetic linkage studies 遗传连锁研究
linkage in cross-impact studies [统计] 交互影响研究中的连接
linkage and association studies 连锁和关联研究
The long arm of chromosome 17 has previously been associated with prostate cancer in family-based linkage studies, the authors explain, but no susceptibility variants have been reported before now.
作者说，17号染色体的长臂以前在家族相关性研究中（被认为）与前列腺癌有关，但是以前没有报道易感变异。
After linkage analysis failed to locate susceptible genes of complex diseases like schizophrenia, it is a better way to process whole-genome association studies.
用传统的家系连锁分析无法对精神分裂症这样的复杂疾病进行基因定位，而全基因组关联分析则为最终发现这些基因提供了较好的策略。
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