The Bush library offers one approach, mostly reflecting the views of his supporters, but Americans will debate the impact of those controversial eight years for a long time.
However, this impulse can become destructive: if you spend a lot of time alphabetizing your spices or setting up eighty categories for your home library, consider simplifying your approach.
Synta, on the other hand, uses the same basic approach that drug companies have used for centuries: taking a library of thousands of chemical compounds, and testing those compounds one by one in the lab until something seems to work.