It works because many cases of muscular dystrophy are caused by mutations in the dystrophin gene (incidentally, one of the longest genes in the body) that make the entire genetic code for the protein shift by one letter.

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Multiple keyboard actuations are now possible (shift plus a letter, for example), though it's not perfect -- things start to get flaky as your second press gets physically close to your first one, which makes some sense considering that the switches are placed at the screen's four corners.

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In this letter, he cites the tremendous culture shift that has happened at the firm.

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