先导化合物(Leading Compounds)是指具有某 种生物活性的化学结构，由于其活性不强，或选择性低，或 吸收性差，或毒性较大等缺点，不能直接药用，但作为新的 结构...
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1 Screening and determination of target compound Screening and determination of the target compound from the active leading compounds is the premise and the foundation in the process of drug discovery and development.
1目标化合物的筛选与确定目标化合物的筛选与确定是药物制备研究的前提和基础，首先要通过各种途径和方法发现先导化合物，通过对其结构进行优化，最终确立制备研究的目标化合物。
参考来源 - 创新药物制备研究的规范化设计·2,447,543篇论文数据，部分数据来源于NoteExpress
Marine natural products have become one of the most important resources of novel leading compounds especially for the critical diseases.
海洋天然产物已成为发现重要先导药物的主要源泉。
A study has shown that compounds found in the fruit protect cells from the ultraviolet radiation emitted by the sun - the leading environmental cause of skin cancer.
一项研究表明，在葡萄中发现的化合物能保护皮肤细胞，防止太阳紫外线的辐射，而紫外线正是诱发皮肤癌的首要环境因素。
Natural anti-inflammatory substances target a much broader range of inflammatory compounds, leading to greater safety and effectiveness.
而自然界里的抗组织胺物质可以抑制多种炎症混合物的产生，会给健康带来更大的安全作用。
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