...肝炎，慢性;拉米夫定耐药;a一干扰素;a1胸腺肤;抗病毒治疗 [gap=1501]Key words; Chronic hepatitis B; Lamivudine resistance; a-interferon; al-thymosin; Antiviral therapy ..
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Patients with chronic hepatitis B developing lamivudine resistance are at high risk of disease progression and death.
对拉米夫定耐药的慢性乙肝患者面临着病情恶化甚至死亡的危险。
To investigate the risk factors of liver failure due to lamivudine resistance in the patients with chronic hepatitis B.
邓洪，顾琳，赵志新， 张晓红，彭晓谋，高志良探讨慢性乙型肝炎患者拉米夫定耐药后出现肝功能衰竭的危险因素。
Results The microarray can identify a single base change of selected lamivudine resistance-related mutation and multiple mutation detection by a single assay as well.
结果我们研制的芯片能同时特异性地检测耐药相关单一或多位点突变。
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