What seems to be the trouble, lady?

有什么麻烦吗，女士？

《柯林斯英汉双解大词典》

The old lady has trouble moving about.

老太太手脚有点不灵了。

《新英汉大辞典》

The face in the picture was that of alovely young lady, and for some reason I had trouble recognizing her from thehalls of Webster’s home, the girl who had caught my attention on first glance.

照片里的是个可人的年轻姑娘，不知怎的，我竟没认出这跟韦伯斯特家走廊放的那张照片是同一个人，这女孩真让我一见钟情。

youdao

But much of the trouble boils down to poor leadership, ie, Lady Ashton.

ECONOMIST: European politics