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knockout mice

  • 敲除小鼠:一种通过基因工程技术敲除或失活某个特定基因的实验小鼠,用于研究基因功能和疾病发生机制。

专业释义英英释义

  • 基因敲除小鼠 - 引用次数:32

    TRPV4-/-knockout mice also show reduced thermal hyperalgesia in inflammatory pain.

    TRPV4基因敲除小鼠也表现出对炎症引起的热痛觉过敏降低。

    参考来源 - TRPV4信号通路在大鼠背根神经节慢性压迫后痛觉过敏的机制
    基因敲除鼠 - 引用次数:4

    In the present study, to reveal the involvement of oxidative stress in hypertension and insulin resistance, we administered angioten-sin II to adrenomedullin knockout mice and examined blood pressure changes and insulin resistance.

    在本实验中,为了揭示氧化应激与高血压和胰岛素抵抗的关系,我们给予肾上腺髓质素基因敲除鼠血管紧张素Ⅱ并检测血压改变与胰岛素抵抗。

    参考来源 - 用基因敲除的方法研究肾上腺髓质素对胰岛素抵抗及肾间质纤维化的保护作用
    abhd2基因

·2,447,543篇论文数据,部分数据来源于NoteExpress

Knockout mouse

  • abstract: A knockout mouse is a genetically engineered mouse in which researchers have inactivated, or "knocked out," an existing gene by replacing it or disrupting it with an artificial piece of DNA. The loss of gene activity often causes changes in a mouse's phenotype, which includes appearance, behavior and other observable physical and biochemical characteristics.

以上来源于: WordNet

双语例句权威例句

  • In addition, the knockout mice might be useful as models to study mania.

    另外基因敲除小鼠可以作为研究躁狂症模型

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  • The upshot was that the knockout mice ate considerably more than the normal animals.

    结果基因敲除基因老鼠正常老鼠更多

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  • Objective To delve into the relationship of blood-lipid to serum bilirubin in ApoE gene-knockout mice.

    目的探讨动脉粥样硬化小鼠血脂血清胆红素之间关系

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更多双语例句
  • When the researchers disabled the gene in mice, they found these knockout mice were leaner than their unaltered counterparts.

    FORBES: Millennium Drug Bodes Well For Industry

  • The first practical application of embryonic stem cells was to provide a way for the gene-targeting trick invented by Dr Capecchi and Dr Smithies to be used to produce adult mice lacking particular genes or knockout mice, as they are now called.

    ECONOMIST: The 2007 Nobel science prizes

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