TRPV4-/-knockout mice also show reduced thermal hyperalgesia in inflammatory pain.
TRPV4基因敲除小鼠也表现出对炎症引起的热痛觉过敏降低。
参考来源 - TRPV4信号通路在大鼠背根神经节慢性压迫后痛觉过敏的机制In the present study, to reveal the involvement of oxidative stress in hypertension and insulin resistance, we administered angioten-sin II to adrenomedullin knockout mice and examined blood pressure changes and insulin resistance.
在本实验中，为了揭示氧化应激与高血压和胰岛素抵抗的关系，我们给予肾上腺髓质素基因敲除鼠血管紧张素Ⅱ并检测血压改变与胰岛素抵抗。
参考来源 - 用基因敲除的方法研究肾上腺髓质素对胰岛素抵抗及肾间质纤维化的保护作用·2,447,543篇论文数据，部分数据来源于NoteExpress
The upshot was that the knockout mice ate considerably more than the normal animals.
其结果是，基因敲除基因的老鼠吃比正常老鼠更多。
The knockout mice (OTR-/-) displayed impaired social behavior, increased aggression and reduced cognitive flexibility leading to resistance to change.
敲除小鼠(OTR -/- )表现出抗变的特点：社会行为受损、攻击性增强、认知灵活性减弱。
In addition, the knockout mice might be useful as a model to study mania, as there is no other animal model available yet.
另外，该基因敲除小鼠可以作为研究躁狂症的模型。现在还没有可用于躁狂症的动物模型。
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