第三代:新开发的大环内酯类 1,酮内酯(Ketolides):如泰利霉素(第一个临床应用 的酮内酯)等; 2,酰内酯(Acylides):TEA-0769, FMA122 FMA-199和 FMA-481等; 3,氮内酯(Azzilides):L-7...
基于14个网页-相关网页
Recently the ketolides have been studied a lot. This kind of structure is not only stable to acid but also without induction drug resistance.
近年来酮内酯是研究较多的大环内酯衍生物,这种结构不但对酸性介质稳定而且无诱导耐药性。
参考来源 - 大环内酯母核引入不同侧链的设计合成·2,447,543篇论文数据，部分数据来源于NoteExpress
Telithromycin, which is the representative of ketolides, has come into market in 2001. It shows very good activity against some macrolide-resistant bacteria.
酮内酯中最具代表性的药物泰利霉素已于2001年成功上市，其对包括大环内酯耐药菌在内的革兰氏阳性菌具有良好的抗菌活性。
The invention concerns a novel therapeutic application of ketolides for preparing pharmaceutical compositions for preventing arterial thrombotic complications related to atherosclerosis.
本发明涉及酮立得在制备用于预防与动脉粥样硬化有关的动脉栓塞并发症的药物组合物中的新治疗应用。
应用推荐