As a result, Mr. Kerbel's venture caters to a relatively small portion of the M.

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After the drug was stopped, mice treated with the anti-angiogenic drug "had more metastases, the metastases occurred more quickly, and they died sooner, " Kerbel says.

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Kerbel says additional drugs may have to be layered on top of Avastin to prevent tumors from developing escape mechanisms--adding to the expense and side effects.

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