Ibrutinib (ibr), a first-in-class, once-daily, oral, covalent inhibitor of Bruton's tyrosine kinase (BTK), is rapidly eliminated from plasma after oral administration (Advani, JCO 2013).

依鲁替尼——首创药物，每天口服一次，布鲁顿酪氨酸激酶（BTK）的共价抑制剂——口服给药之后可快速从浆细胞内清除。

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In 1999, Nakagawa was involved in treating two employees of JCO, a nuclear fuel cycle company, whose mishandling of uranium resulted in massive doses of radiation. Both employees eventually died.

1999年，中川曾卷入治疗JCO公司的两名员工，经营核燃料回收的JCO公司当时由于对铀的不正确操作导致大剂量的核辐射，导致两名员工最终身亡。

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Many organizations were involved in the JCO criticality accident processing, accident analysis, emergency radiation monitoring, environmental and health effect evaluation and public communication.

事故发生后日本有关部门和机构对事故处理、事故分析、应急监测、事故影响评价、公众沟通等方面做了大量工作。

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JCO, for example, was a straggler kept alive by Japan's powerful nuclear lobby and its friends at the Ministry of International Trade and Industry.

ECONOMIST: The land of disappointments

JCO, the company that operates the uranium-processing plant at Tokaimura, had quietly compiled a manual that encouraged workers to cut corners, quite illegally, to reduce costs.

ECONOMIST: All over in a flash

The AWSJ went further in its two front-page stories and concluded that "the enormous pressure JCO felt to cut costs and compete with overseas rivals" was ultimately to blame.

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