In February 1785 The Times listed opium from Smyrna (now Izmir) between oil from Leghorn (Livorno) and peas from Dantzic (Gdansk) in its roundup of goods unloaded at the port of London.
But I do not think it has ever occurred to me with such poignancy as in Izmir, the city the Greeks once called Smyrna, before their 3, 000-year-old living presence in Asia Minor was all but expunged.