Some patients may become very isolated and depressed.

有些病人可能变得非常孤独和抑郁。

《柯林斯英汉双解大词典》

It may make us feel isolated and incompetent.

它可能会让我们感到孤立和无能。

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They feel irritable and depressed, often isolated and lonely.

他们感到烦躁和抑郁，经常感到孤立和孤独。

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It is of an island people cut off from the wider world - isolated and exposed.

BBC: Chelsea Flower Show and our island mentality

Syria will feel even more isolated and embarrassed if its sole solid ally is Iran.

ECONOMIST: As the turmoil persists, more Syrians are leaving or hiding

Luckily for you, there are thousands of other entrepreneurs who also feel isolated and lonely.

FORBES: Starting Up? Embrace Your (Sometimes Scary) New Normal