... 本报讯 英国Harrison等进行的研究结果表明,检测多发性骨髓瘤(MM)患者的13q14缺失,可采用间期荧光原位杂交(interphase FISH)技术。(Br J Hematok 2003,120∶944)
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Conclusion: Interphase FISH plays an important role in the diagnosis, classification and subdivision of NHL, especially in the diagnosis of small cell lymphoma like MCL, SLL and FL, lymphoid follicular and FL are also difficult to be differentiated diagnosed.
结论:间期核FISH方法所提供的细胞遗传学异常改变的依据对于鉴别淋巴瘤的类型、亚型以及病变的良恶性质有重要的诊断性价值,尤其针对形态学相似的小细胞性淋巴瘤亚型的鉴别、淋巴结反应性增生与FL之间的鉴别。
参考来源 - 分子细胞遗传学检测在淋巴瘤诊断中的应用·2,447,543篇论文数据,部分数据来源于NoteExpress
Conclusion Interphase FISH assay is a rapid and sensitive tool for detecting IGH abnormalities.
结论间期FISH是检测igh基因异常的快速和敏感的手段。
Methods Multiplex FISH was used in combination with conventional cytogenetics (CC) and interphase FISH to study 14 cases of AML with complex karyotypic abnormalities.
方法联合应用常规细胞遗传学、间期荧光原位杂交技术和多重荧光原位杂交技术对14例伴有复杂核型异常的aml患者进行研究。
To make prenatal diagnosis of chromosome aneuploidies by FISH analysis of chromosome-specific probes in interphase amniocytes.
应用染色体特异性探针对羊水间期细胞进行FISH分析。
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