Now, there are a couple of ways that can go; one that was certainly important and again it's for something that Hanson emphasizes, is what he calls internal colonization.
Another paper in the Annals of Internal Medicine calls chronic Lyme a "functional somatic syndrome, " similar to other nebulous ailments like Gulf War Syndrome, chronic fatigue and fibromyalgia.
Example: Your customer service rep may resolve 50 calls a week, but that same rep may have drawn on additional internal or external resources to handle those calls.