First and foremost, some people shirk their duty of financially supporting their old and helpless parents due to their own interests.

首先，有些人由于自己的利益逃避赡养他们年迈无助父母的责任。

youdao

First of all, China has no major Allies, with the possible exception of Russia, which clearly seeks to protect its own interests first and foremost.

首先，中国没有大的盟友。俄罗斯明显不可能，因为它很明确地表示首先要保护自身的利益。

youdao

Banks restates his backing for Dobson, who's "got the interests of London at heart, first and foremost".

BBC: Ambassador Banks

Consequently, his speech imperils the real interests that the US has in the region - first and foremost, the US's interest in securing its national security.

CENTERFORSECURITYPOLICY: Obama's abandonment of America

Mr Ozal claimed PPI "might have been victim of those whose purpose is first and foremost to undermine the Turkish Cypriot economy and the interests of Turkey".

BBC: Asil Nadir trial: Turkish President wrote to Thatcher