First-line treatment is the initial treatment given to a patient.

一线治疗是对病人进行的最初治疗。

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In fact, the initial specification is a standard (RFC821) first published in 1982 before the Web as we know it even existed.

事实上，最初的规范是1982年发布的标准(RFC 821)，当时我们还不知道有Internet。

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The first element contains a connection instance for the initial connection.

第一个元素包含初始连接的一个连接实例。

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Thirteen such deals have generated an average first-day gain of 20%, compared with a 14% first-day pop for all initial offerings, according to Ipreo, a market intelligence firm.

WSJ: Pinnacle Foods IPO to Test Investor Appetite

Bitdefender, the 670-person Bucharest-based security software firm, could be the first initial public offering of a Romania-based tech firm.

FORBES: Will Bitdefender Be Romania's First Tech IPO?

The property market has changed dramatically since 1997, when Mr Paim de Andrade led the first initial public offering of a Brazilian housebuilder (Rossi Residencial).

ECONOMIST: A housing boom has investors swooning