A high initial dose is key to the success of the treatment.

最初的高剂量是治疗成功的关键。

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We shall initiate your treatment right away, with an initial dose of just 10 milligrams.

我们将马上开始对你的治疗，初始的剂量只有10毫克。

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CONCLUSIONS: Precision pharmaceutical care can effectively provide patients with optimal dosing regimens, predict initial dose and optimal therapeutic concentrations, improve efficacy and reduce ADR.

结论：精准药学服务可有效地为患者提供最佳的给药方案，预测初始治疗剂量及最佳治疗浓度，提高药物治疗效果、减少药品不良反应。

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He was found to have large chemical burns on both arms and his lawyer reported that the 55-year-old continued to move and mouth words more than 20 minutes after the initial dose.

BBC: A coroner found chemical burns on Diaz's arms

This report will further examine this susceptibility by analyzing temporal trends in childhood cancer in populations exposed to low-dose nuclear power plant emissions 5-10 years after initial exposure.

FORBES: French System For Cleaning Fukushima Water Blamed For Leukemia, Polluted Beaches In Europe