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Italy's National Institute of Geophysics and Volcanology (INGV) said the quake struck at 15:48 (14:48 GMT), with its epicentre in Garfagnana.
BBC: Italy: Earthquake hits near Bologna
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Alessandro Amato of the INGV said the latest tremor "came out of nowhere", and described it as a classic earthquake for the area - "medium-strong" and "fairly shallow".
BBC: Italy: Earthquake hits near Bologna
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Raffaele Azzaro, first researcher at INGV-CT, told CNN that one local faultline has moved by as much as 17 centimeters in one day, and currently moves at a rate of around three centimeters each year.
CNN: Keeping track of Etna's pulse