Backgroud: Indoleamine- 2, 3 -Dioxygenase(INDO) is one of the rate-limiting enzyme in tryptophan catabolism, which can induce region immune tolerance by many mechanism after its expression is enhanced, to create the suitable condition for development of tumor.
背景:吲哚胺-2,3-双加氧酶(INDO)是人体细胞内色氨酸代谢限速酶,其表达增强后可以通过多种机制诱导局部免疫耐受,为肿瘤的发生、发展乃至转移创造适宜的条件。
参考来源 - 吲哚胺·2,447,543篇论文数据,部分数据来源于NoteExpress
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