Betulin and Betulinic acid treatment could decrease serum AST, ALT activities and hepatic MDA level significantly, and critically increased hepatic GSH and CAT levels.

预防给予不同剂量的白桦酯醇或白桦酯酸可明显降低小鼠血清中alt、AST和肝脏中MDA活性，提高GSH和CAT水平。

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Results: Levels of blood glucose, ALT, AST in Adogold groups significantly decreased compared with control group, but level of liver glucose was significantly increased.

结果：与对照相比，奥德金实验组血葡萄糖含量显著降低，肝葡萄糖含量显著升高，血清alt、AST水平明显降低。

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Results SOD activity decreased significantly (P<0.05), MDA and AST concentration increased remarkably (P<0.05, P<0.05), and abnormal morphological changes of hepatocytes were obvious during HPRI.

结果HPRI时，SOD活性显著下降（P＜0.05），MDA 含量和AST 活性明显升高（P＜0.05，P＜0.05），肝细胞形态发生异常变化。

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The most common adverse reactions in patients treated with KYNAMRO that led to treatment discontinuation and occurred at a rate greater than placebo were: injection site reactions (5.0%), alanine aminotransferase (ALT) increased (3.4%), flu-like symptoms (2.7%), aspartate aminotransferase (AST) increased (2.3%), and liver function test abnormal (1.5%).

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