Furthermore, these miRNAs repress multiple target genes, with downregulation of individual targets only partially recapitulating the total miRNA effects. These targets regulate various cellular processes, including cell cycle, epithelial-mesenchymal transition (EMT), epigenetic regulation and vesicular transport.
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To ensure genome integrity and prevent aneuploidy, eukaryotes have evolved an integrated protective mechanism, including cell cycle control, checkpoint control, and DNA repair.
真核生物对维持基因组的稳定性及防止非整倍体的产生，有其一套完整的保护机制，即细胞周期调控、检验点调控以及对损伤DNA的修复。
We analyze some genes including cell cycle, apoptosis, stress and inflammation, which are confirmed by the real time RT-PCR, and the results are corresponded to that of cDNA microarray.
我们对部分细胞周期、细胞凋亡、细胞应激与炎症反应相关基因进行了分析并用实时荧光定量pcr进行了验证，证实了基因芯片结果的可靠性。
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