Genetic variation is major study content in conservation genetics. In small population, genetic variation loss because of bottleneck effect, inbreeding, founder effect, and genetic drift.

遗传变异性是遗传保护研究的主要内容，在小种群中，往往由于瓶颈效应、近亲繁殖、奠基者效应和遗传漂变等使得遗传变异性减少。

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One study in Africa has already found that inbreeding has an effect on people's propensity to develop tuberculosis.

ECONOMIST: Inbreeding: Consanguinity costs | The