They found that mice with an inactive version of the gene scratched less when exposed to itchy things than mice with an active gene.
他们发现,同样用瘙痒的东西刺激白鼠,此基因处于非活动状态的白鼠明显要比此基因处于活动状态的白鼠搔痒次数少。
The researchers hope that understanding more about the gene's mutations and the structure of the protein may lead to drug treatments to help ensure that mutant copies of the gene are inactive.
研究者们希望,通过对该基因突变和相关蛋白结构的深入了解可以开发出有效的药物治疗来抑制突变基因的激活。
Basically, you're introducing this gene into cells that when you give the right inactive drug that will cause the cell to make chemicals that kill it.
概括来说,当你把这个自杀基因导入,含有特定未激活药物的细胞时,二者作用就使细胞生成了,可以杀死自己的化合物
It's a gene that allows you to deliver a drug that's not active but the gene causes that active - that inactive drug to be converted into an active form that kills the cell.
这一方法利用该基因激活,另一种已经导入细胞的非活性药物,来杀死肿瘤细胞
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