Objective: to investigate the effects of the expression of exogenous brain derived neurotrophic factors (BDNF) on injured spinal cord following in vivo adenoviral gene transfer to the cord.
目的:研究腺病毒介导的脑源性神经营养因子(BDNF)基因在大鼠损伤脊髓内的表达规律,观察外源性BD NF对损伤脊髓的作用。
Results Assay of joint lavages confirmed the in vivo expression of biologically active hIL1Ra and hIL-10 and gene expression was not lost 14 days after transfer.
结果:外源基因转移后14天表达尚很稳定,治疗基因在受体关节的滑膜衬里部位表达。
Objective . This study was undertaken to test the feasibility of local gene transfer in vivo using polylysine- coated balloon catheter.
目的:研究多聚赖氨酸包被的球囊导管作在体定向基因转导的可行性。
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