6、咪喹莫特(imiquimod)：是一种新型的外用免疫调节剂。研究表明，咪喹莫特及其他咪唑喹啉胺类药物均具有抗病毒和抗肿瘤能力，这种抗病毒和抗肿瘤能力并...
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Imiquimod Cream 咪喹莫特乳膏 ; 用自制的眯喹莫特乳膏 ; 喹莫特乳膏 ; 咪喹莫特
Imiquimod Crem 咪喹莫特乳膏
Imiquimod&Cream 咪喹莫特乳膏
Imiquimod Related Compound D 咪喹莫特杂质D
Imiquimod Related Compound A 咪喹莫特相关物质A
The results showed all the studied TLR agonists,especially TLR3 agonist(polyinosinic acid-polycytidylic acid,PIC) and TLR4 agonist(lipopolysaccharide,LPS),could promote the maturation and IL-12 production of E7-loaded mdDCs(E7-mdDCs). The effect of TLR7 agonist(imiquimod) and TLR9 agonist(cytidylyl phosphate guanosine oligoneuleotid,CpG ODN) were relatively weak.
结果显示,所研究的TLR激动剂均能促进mdDCs功能分化及成熟,促进负载E7多肽的mdDCs(以下简称E7-mdDCs)分泌IL-12,尤以TLR3的激动剂聚肌胞苷酸(polyinosinicacid-polycytidylic acid,PIC)和TLR4的激动剂脂多糖(lipopolysaccharide,LPS)刺激作用最强,而TLR7的激动剂咪喹莫特及TLR9的激动剂胞嘧啶鸟嘌呤核苷酸序列(cytidylyl phosphate guanosine oligoneuleotid,CpG ODN)的作用相对较弱。
参考来源 - Toll样受体激动剂和RNA干预技术对HPV 6b/11型感染的抑制作用研究·2,447,543篇论文数据，部分数据来源于NoteExpress
OBJECTIVE To prepare imiquimod-loaded solid lipid nanoparticles and investigate their properties and transdermal permeation.
目的制备咪喹莫特固体脂质纳米粒，并考察其理化性质及其对透皮的影响。
Objective To observe the clinical efficacy and safety of 5% imiquimod cream in topical treatment of condyloma acuminatum and to compare it with 2.5% fluorouracil(5-FU) cream.
目的评价5%咪喹莫特乳膏治疗尖锐湿疣的疗效和安全性，并与2.5%5-氟脲嘧啶乳膏进行对照。
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