This article reviews the effect of biotherapy in ra including tumor necrosis factor inhibitor, IL-1inhibitor, stem cell transplantation genetic therapy and so on.

本文综述了包括肿瘤坏死因子抑制剂、白细胞介素1抑制剂、干细胞移植及基因治疗等生物治疗在类风湿性关节炎治疗中的作用。

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In recent years studies, it has been shown that IL-18 participated in the genesis of RA, which has become a new hot spot of RA study.

近年发现，白细胞介素- 18可作用于RA发病的多个参与因素，成为研究RA的新热点。

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Objective To investigate the circadian variation of serum interleukin 6 (IL 6) and cortisol and their clinical value in rheumatoid arthritis (RA) patients.

目的研究类风湿关节炎（RA）患者血清白细胞介素（IL） 6、皮质醇节律及其临床意义。

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