Fibrosis, if it becomes severe, can lead to stiffening or thickening of portions of the heart, which can contribute to irregular heart function and, eventually, heart failure.

心肌纤维化，一旦严重，会导致心脏变厚变粗糙，引发心脏功能紊乱，最终心衰竭。

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If a wall is thick, it becomes a more severe cooling issue.

壁太厚会导致更严重的冷却问题。

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If the U. S. Federal Reserve becomes concerned about the inflation resulting from higher import prices, it might raise interest rates, which could lead to another severe hit to the economy.

如果美联储开始关心由于通货膨胀产生的输入高价，可能提高利率，那样将更沉重的打击经济。

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"At this stage then it becomes acutely difficult, if not quite impossible, to set a budget and precept which is acceptable without causing a severe level of disappointment within the police service, difficulties amongst our partners and anger from the public that we exist to serve, " Mr Michael said.

BBC: Alun Michael